Connecting psychophysical performance to neuronal response properties I: Discrimination of suprathreshold stimuli

One of the major goals of sensory neuroscience is to understand how an organism's perceptual abilities relate to the underlying physiology. To this end, we derived equations to estimate the best possible psychophysical discrimination performance, given the properties of the neurons carrying the sensory code.We set up a generic sensory coding model with neurons characterized by their tuning function to the stimulus and the random process that generates spikes. The tuning function was a Gaussian function or a sigmoid (Naka-Rushton) function.Spikes were generated using Poisson spiking processes whose rates were modulated by a multiplicative, gamma-distributed gain signal that was shared between neurons. This doubly stochastic process generates realistic levels of neuronal variability and a realistic correlation structure within the population. Using Fisher information as a close approximation of the model's decoding precision, we derived equations to predict the model's discrimination performance from the neuronal parameters. We then verified the accuracy of our equations using Monte Carlo simulations. Our work has two major benefits. Firstly, we can quickly calculate the performance of physiologically plausible population-coding models by evaluating simple equations, which makes it easy to fit the model to psychophysical data. Secondly, the equations revealed some remarkably straightforward relationships between psychophysical discrimination performance and the parameters of the neuronal population, giving deep insights into the relationships between an organism's perceptual abilities and the properties of the neurons on which those abilities depend

One "shape" fits all: The orientation bandwidth of contour integration

The ability of human participants to integrate fragmented stimulus elements into perceived coherent contours (amidst a field of distracter elements) has been intensively studied across a large number of contour element parameters, ranging from luminance contrast and chromaticity to motion and stereo. The evidence suggests that contour integration performance depends on the low-level Fourier properties of the stimuli. Thus, to understand contour integration, it would be advantageous to understand the properties of the low-level filters that the visual system uses to process contour stimuli. We addressed this issue by examining the role of stimulus element orientation bandwidth in contour integration, a previously unexplored area. We carried out three psychophysical experiments, and then simulated all of the experiments using a recently developed two-stage filter-overlap model whereby the contour grouping occurs by virtue of the overlap between the filter responses to different elements. The first stage of the model responds to the elements, while the second stage integrates the responses along the contour. We found that the first stage had to be fairly broadly tuned for orientation to account for our results. The model showed a very good fit to a large data set with relatively few free parameters, suggesting that this class of model may have an important role to play in helping us to better understand the mechanisms of contour integration

Contour integration: Psychophysical, neurophysiological, and computational perspectives

One of the important roles of our visual system is to detect and segregate objects. Neurons in the early visual system extract local image features from the visual scene. To combine these features into separate, global objects, the visual system must perform some kind of grouping operation. One such operation is contour integration. Contours form the outlines of objects, and are the first step in shape perception. We discuss the mechanism of contour integration from psychophysical, neurophysiological, and computational perspectives

Self-healing Web service composition with HTN planners

Web services have become a prominent paradigm for building of both inter and intra-enterprise business processes. These processes are composed from existing Web services based on defined requirements. Standards and techniques have been developed to aid in the dynamic composition of services. However, these approaches are limited when it comes to the handling of unexpected events. This dissertation presents the results of experiments that investigated numerous problems related to Web service composition processes. Based on the investigation, a fault taxonomy was formulated. Faults were grouped into three broad categories, each representing a distinct problem stage. The investigation into faults gave rise to the issue of fault recovery and continued process execution. A list of requirements for self-healing Web service composition was identified, while a new self-healing cycle was exploited based on the MAPE cycle (Monitor, Analyzer, Planner, Executive). The proposed self-healing composition cycle consists of three modules: Plan Generation Module, Plan Execution Module and Failure Analysis Module. The plan execution module, consisting of the execution and run-time monitoring phases, and the failure analysis module, consisting of the analysis and sensemaking phases, were found to be vital to self-healing Web service composition. Self healing Web service composition and the goal of self-healing were achieved through the use of Hierarchical Task Network (HTN) planning systems.Dissertation (MSc)--University of Pretoria, 2009.Computer Scienceunrestricte

Contour extracting networks in early extrastriate cortex

Neurons in the visual cortex process a local region of visual space, but in order to adequately analyze natural images, neurons need to interact. The notion of an ?association field? proposes that neurons interact to extract extended contours. Here, we identify the site and properties of contour integration mechanisms. We used functional magnetic resonance imaging (fMRI) and population receptive field (pRF) analyses. We devised pRF mapping stimuli consisting of contours. We isolated the contribution of contour integration mechanisms to the pRF by manipulating the contour content. This stimulus manipulation led to systematic changes in pRF size. Whereas a bank of Gabor filters quantitatively explains pRF size changes in V1, only V2/V3 pRF sizes match the predictions of the association field. pRF size changes in later visual field maps, hV4, LO-1, and LO-2 do not follow either prediction and are probably driven by distinct classical receptive field properties or other extraclassical integration mechanisms. These pRF changes do not follow conventional fMRI signal strength measures. Therefore, analyses of pRF changes provide a novel computational neuroimaging approach to investigating neural interactions. We interpreted these results as evidence for neural interactions along co-oriented, cocircular receptive fields in the early extrastriate visual cortex (V2/V3), consistent with the notion of a contour association field

Conferences in the time of COVID: notes on organizing and delivering the first Brain Conference

To further fulfil their missions of promoting teaching, education and research in neurology and related clinical-academic disciplines, the Guarantors of Brain and the Brain journal family invited delegates to the first Brain Conference in Spring of this year. This event aimed to deliver excellent teaching and scientific presentations across a broad spectrum of neuroscience fields, with the key aim of making the content as accessible as possible. We hoped to capitalize on the benefits of an online format, whilst trying to capture a little of the joy of the in-person meeting. This article reports on the approach and practical choices made to achieve these goals, and we hope this will provide some guidance and advice to others organizing their own online conference

Understanding environmental justice capital in China — a new framework to study environmental justice in contexts

Environmental justice has drew worldwide attention since the 1982 protest in USA to against duping toxic waste. In the globalization era, worldwide scholars and environmental activists are actively engaged in related studies and social movements. However, these researches and movements usually ignore the influences of local contexts on local environmental justice configurations, including related researches in China. Whilst, evidences have been provided that different forms of capital from contexts, such as economic, social, political, natural capital and cultural capital, will affect the local concept of environmental justice. That is to say environmental justice should have different discourse from what has been researched in western countries in different contexts. Thus, this research will discuss the common ground of environmental justice study framework and promote the new conceptual framework “environmental justice capital” for having a better understanding environmental justice in contexts. Additionally, the framework of “environmental justice capital” will be put in Chinese contexts as a preliminary discussion to get an initial image of environmental justice in China

High-Temperature Transport Properties of Yb4−xSmxSb3

Polycrystalline L4Sb3 (L = La, Ce, Sm, and Yb) and Yb4−x Sm x Sb3, which crystallizes in the anti-Th3P4 structure type (I-43d no. 220), were synthesized via high-temperature reaction. Structural and chemical characterization were performed by x-ray diffraction and electronic microscopy with energy-dispersive x-ray analysis. Pucks were densified by spark plasma sintering. Transport property measurements showed that these compounds are n-type with low Seebeck coefficients, except for Yb4Sb3, which shows semimetallic behavior with hole conduction above 523 K. By partially substituting Yb by a trivalent rare earth we successfully improved the thermoelectric figure of merit of Yb4Sb3 up to 0.7 at 1273 K

What Is the Professional Identity of Allied Health Managers?

Objective: This paper explores the professional identity (PI) of Allied Health Managers (AHMs) and how their identity is typically constructed. Methods: A qualitative research methodology utilising semi-structured interviews was employed for this research. Thematic analysis was used to extract relevant data from the transcripts. Settings: The study was undertaken in five acute hospitals within one of the largest metropolitan Local Health Districts in New South Wales, Australia. A total of sixteen AHMs and deputy AHMs were interviewed. Results: Three key themes identified were: PI of AHM, motivation of becoming a manager, and construction of their identity. Factors motivating AHMs to follow a management pathway were identified as being a natural progression and having interest in high-level decision-making. Despite AHMs sharing similar role conflict as the medical managers, they adapted to hybrid manager roles with minimal resentment. They also adopted to the hybrid manager role with a positive, realistic and flexible perspective. Conclusion: Despite facing role conflict as a hybrid-professional-manager, AHMs manage the transition from clinicians to managers with a positive approach. This indicates that AHMs may require certain skills or characteristics to successfully construct their PI